104 compounds, with the sources attached.
GLP-1 medicines, peptides, hormones, and supplements, each with what the human evidence measures, what remains unknown, and safety notes. Human trials, animal studies, and lab findings are labeled separately. Identification and education only: no dosing advice, no purchasing links.
Showing all 104 guides
Semaglutide
GLP-1 receptor agonist (Ozempic/Wegovy)
Randomized human evidenceGLP-1 & MetabolicTirzepatide
GIP/GLP-1 dual agonist (Mounjaro/Zepbound)
Randomized human evidenceGLP-1 & MetabolicRetatrutide
GGG triple agonist, investigational
Human randomized trialsGLP-1 & MetabolicLiraglutide
Daily GLP-1 agonist (Saxenda/Victoza)
Approved-product clinical evidenceGLP-1 & MetabolicCagrilintide
Amylin analog, investigational
Human randomized trialsGLP-1 & MetabolicSurvodutide
Glucagon/GLP-1 dual agonist, investigational
Human randomized trialsGLP-1 & MetabolicAOD-9604
HGH fragment 176-191 analog
Animal studies; limited clinical certaintyGLP-1 & Metabolic5-Amino-1MQ
NNMT inhibitor, small molecule
Cell and animal evidenceGLP-1 & MetabolicMOTS-c
Mitochondrial-derived metabolic peptide
Cell and animal evidenceGLP-1 & MetabolicTesofensine
Triple monoamine reuptake inhibitor
Human trial with an Expression of ConcernHealing & RecoveryBPC-157
Body-protection compound, gastric pentadecapeptide
Limited human evidenceHealing & RecoveryTB-500
Thymosin beta-4 fragment
Human evidence not establishedHealing & RecoveryBPC-157 / TB-500 blend
BPC-157 and TB-500 combination
Combination evidence limitedHealing & RecoveryGHK-Cu
Copper tripeptide
Preclinical evidence highlightedHealing & RecoveryKPV
α-MSH fragment, gut & inflammation research
Cell and mouse evidenceHealing & RecoveryARA-290
EPO-derived research peptide
Early human trials · mixed outcomesHealing & RecoveryPentosan Polysulfate
Semi-synthetic glycosaminoglycan
Approved oral product; route-specific evidenceHealing & RecoveryLarazotide
Tight-junction regulator peptide
Human randomized trial evidenceGrowth Hormone AxisCJC-1295 (no DAC)
GHRH analog (Mod GRF 1-29)
Evidence cannot be transferredGrowth Hormone AxisCJC-1295 (DAC)
Long-acting GHRH analog
Early randomized human studiesGrowth Hormone AxisIpamorelin
Selective ghrelin-receptor GH secretagogue
Human trial in a different settingGrowth Hormone AxisCJC-1295 / Ipamorelin
Common combined GH-axis vial
Combination evidence not establishedGrowth Hormone AxisSermorelin
GHRH 1-29 analog
Human physiology; historical product approvalGrowth Hormone AxisTesamorelin
Stabilized GHRH analog (Egrifta)
Approved indication · product-specificGrowth Hormone AxisHexarelin
GH secretagogue hexapeptide
Small human physiology studiesGrowth Hormone AxisGHRP-2
GH-releasing hexapeptide
Small human studies; FDA safety concernsGrowth Hormone AxisGHRP-6
GH-releasing hexapeptide, appetite effects
Small human physiology studiesGrowth Hormone AxisMK-677 (Ibutamoren)
Oral ghrelin mimetic (non-peptide)
Human randomized trials; important safety signalsGrowth Hormone AxisHGH (Somatropin)
Recombinant human growth hormone
Approved-product clinical evidenceLongevity & MitochondrialNAD+
Nicotinamide adenine dinucleotide
Limited human infusion researchLongevity & MitochondrialEpithalon
Telomerase-research tetrapeptide
Preclinical research and a small human biomarker studyLongevity & MitochondrialSS-31 (Elamipretide)
Mitochondrial-targeted tetrapeptide
Approved indication · accelerated approvalLongevity & MitochondrialHumanin
Mitochondrial-derived peptide
Preclinical and observational evidenceLongevity & MitochondrialFOXO4-DRI
Senolytic research peptide
Cell and mouse evidenceLongevity & MitochondrialGlyNAC
Glycine + N-acetylcysteine combination
Small randomized human trialsCognitiveSemax
ACTH-derived research peptide
Mainly preclinical evidence in this guideCognitiveSelank
Tuftsin-derived research peptide
Limited human and preclinical evidenceCognitiveDihexa
Angiotensin IV-derived cognitive research compound
Cell and animal evidenceCognitiveCerebrolysin
Porcine-derived neuropeptide preparation
Human trials with mixed resultsCognitiveP21
CNTF-derived research peptide
Preclinical neurotrophic researchSkin, Hair & TanningMelanotan I
α-MSH analog (afamelanotide)
Human studies; approved product-specific useSkin, Hair & TanningMelanotan II
α-MSH analog, tanning research
Very limited early human researchSkin, Hair & TanningPTD-DBM
Wnt/β-catenin hair-research peptide
Preclinical hair and wound modelsSkin, Hair & TanningZn-Thymulin
Zinc-thymulin hair-research complex
Preclinical biology; small exploratory hair reportImmuneThymosin Alpha-1
Thymic immune-modulating peptide
Human randomized trials exist, including a large negative sepsis trial. Healthy-user prevention and longevity benefits remain unestablished.ImmuneThymulin
Zinc-dependent thymic hormone
Human physiology evidence; very limited direct evidence for therapeutic thymulin administration.ImmuneLL-37
Human cathelicidin antimicrobial peptide
Topical human trials give mixed results; evidence for systemic wellness treatment is inadequate.Sexual HealthPT-141 (Bremelanotide)
Melanocortin agonist (Vyleesi)
Two placebo-controlled phase III trials support improvements in desire and related distress for the labeled population.Sexual HealthKisspeptin-10
GnRH-axis signaling peptide
Small human physiology studies; therapeutic benefit and long-term safety remain uncertain.Sexual HealthOxytocin
Neuropeptide hormone
Established obstetric medicine; small sexual-function trials have not shown a clear advantage over placebo.Hormones & TRTTestosterone Cypionate
Injectable testosterone ester
Established replacement use; clinical benefit depends on diagnosis, formulation and the outcome being measured.Hormones & TRTTestosterone Enanthate
Injectable TRT ester
Established replacement therapy; product trials largely confirm testosterone exposure rather than universal improvement in wellbeing.Hormones & TRTTestosterone Propionate
Short-ester injectable testosterone
Human exposure studies exist, but robust modern head-to-head clinical-outcome evidence is limited.Hormones & TRTTestosterone Undecanoate
Long-ester testosterone (Aveed / Jatenzo)
Approved-product trials establish replacement exposure; selected trials assess symptoms in men with documented deficiency.Hormones & TRTTestosterone Cream
Transdermal testosterone preparation
Replacement evidence exists, but compounded creams need separate quality and exposure assessment.Hormones & TRTTestosterone (female HRT)
Low-dose testosterone in women's HRT
Sexual-function trials exist; long-term safety and broader symptom claims remain uncertain.Hormones & TRTEnclomiphene
Oral selective estrogen receptor modulator
Randomized trials demonstrate endocrine effects; clinical-outcome and long-term safety evidence remain incomplete.Hormones & TRTClomiphene (Clomid)
Oral selective estrogen receptor modulator
Established ovulation-induction use; smaller trials support hormone changes in selected men.Hormones & TRTTamoxifen (Nolvadex)
Oral SERM
Strong clinical evidence in defined breast-cancer settings; much smaller studies for other hormone-related uses.Hormones & TRTAnastrozole
Aromatase inhibitor — estrogen management
Large oncology trials exist. Male hormone studies show endocrine changes and a meaningful bone-health caution.Hormones & TRTHCG
Human chorionic gonadotropin — LH analog
Approved clinical uses in selected reproductive disorders; no established obesity-treatment benefit.Hormones & TRTGonadorelin
GnRH analog
Human fertility evidence exists for specific hypothalamic conditions and controlled pulsatile delivery.Hormones & TRTDHEA
Adrenal androgen precursor (oral)
Human trials do not establish broad anti-aging or vitality benefits from routine oral supplementation.Hormones & TRTEstradiol
Bioidentical estrogen (patch / injection / cream)
Estrogen therapy has established menopausal symptom benefits; formulation and patient context determine the benefit-risk discussion.Hormones & TRTProgesterone
Bioidentical progesterone (oral / cream)
Established oral-product evidence for endometrial protection; symptom studies are more population-specific.Hormones & TRTLevothyroxine (T4)
Thyroid hormone replacement
Established hypothyroidism treatment; benefit is less clear in some subclinical presentations.Hormones & TRTLiothyronine (T3)
Active thyroid hormone
Established thyroid-hormone activity; adding T3 has not consistently improved patient outcomes in controlled studies.SleepDSIP
Delta sleep-inducing peptide
Small, older human sleep studiesSleepEpitalon (nightly)
Pineal-axis tetrapeptide
Preclinical research and a small human biomarker studyOtherL-Carnitine (injectable)
Fatty-acid transport amino acid derivative
Established deficiency-treatment indications; no reliable inference that injecting more produces greater fat loss in someone without deficiency.OtherMethylene Blue
Mitochondrial electron-cycling compound
Approved antidote use; preliminary human cognition research, without established routine nootropic benefit.OtherGlutathione
Glutathione tripeptide
Human oral studies show biomarker effects; broad wellness outcomes and injectable equivalence remain unestablished.OtherB12 (Methylcobalamin)
Injectable B-vitamin
Established vitamin-deficiency biology; separate, disease-specific methylcobalamin research does not validate generic energy claims.OtherLipo-C (MIC + B12)
Lipotropic injection blend
Ingredient physiology exists; convincing controlled weight-loss evidence for the exact blend was not identified.GLP-1 & MetabolicMazdutide
GLP-1 / glucagon dual agonist, investigational
Human phase 3 evidenceGLP-1 & MetabolicOrforglipron
Oral GLP-1 agonist; Foundayo is an approved product
FDA-approved product; phase 3 trialsGLP-1 & MetabolicPramlintide
Amylin analog (Symlin)
Approved-product evidenceGLP-1 & MetabolicEcnoglutide
GLP-1 receptor agonist, investigational
Human phase 3 evidenceGLP-1 & MetabolicSLU-PP-332
ERR agonist research compound
Cell and mouse evidenceHealing & RecoveryPentadeca Arginate (PDA)
BPC-related arginate formulation
Developer announcement; clinical evidence gapHealing & RecoveryVIP
Vasoactive intestinal peptide
Human trials; results depend on setting and routeHealing & RecoveryThymosin Beta-4
Full-length thymosin beta-4 peptide
Study-specific evidenceGrowth Hormone AxisMGF
Mechano growth factor (IGF-1 splice variant)
Conflicting cell and animal evidenceGrowth Hormone AxisPEG-MGF
PEGylated long-acting mechano growth factor
Preclinical context; direct human evidence gapGrowth Hormone AxisIGF-1 LR3
Long-acting insulin-like growth factor analog
Animal pharmacologyGrowth Hormone AxisIGF-1 DES
Shortened IGF-1 variant
Animal pharmacologyGrowth Hormone AxisFollistatin 344
Myostatin-binding research protein
Early human gene-therapy study; product mismatchLongevity & MitochondrialRapamycin (Sirolimus)
mTOR inhibitor, longevity research
Prescription evidence; early aging trialsLongevity & MitochondrialMetformin
Biguanide, metabolic & longevity research
Established diabetes use; uncertain longevity benefitLongevity & MitochondrialNMN
Nicotinamide mononucleotide (NAD+ precursor)
Early human metabolic researchLongevity & MitochondrialNicotinamide Riboside
NAD+ precursor vitamin B3 derivative
Randomized human studies; mixed outcomesLongevity & MitochondrialSpermidine
Polyamine investigated in autophagy research
Randomized human evidence; memory benefit uncertainLongevity & MitochondrialFisetin
Flavonoid investigated in senescence research
Preclinical senescence research and limited human clinical studiesLongevity & MitochondrialUrolithin A
Gut metabolite investigated in mitochondrial research
Randomized human muscle trialsCognitiveBromantane
Bromantane research compound
Limited clinical and laboratory studiesCognitiveNoopept
Nootropic dipeptide research compound
Limited clinical and preclinical evidenceCognitiveCortexin
Porcine cortical neuropeptide preparation
Limited human stroke trialsSkin, Hair & TanningSNAP-8
Acetyl octapeptide-3, topical anti-wrinkle research
Manufacturer-led cosmetic evidenceSkin, Hair & TanningArgireline
Acetyl hexapeptide-8, topical cosmetic peptide
Small randomized topical studiesImmuneThymogen
Glutamyl-tryptophan immune dipeptide
Small, older human studies; little independently replicated evidence for contemporary wellness claims.ImmuneThymalin
Thymic peptide immune-regulating preparation
Limited clinical reports with important design and reporting uncertainty; mechanistic findings are preliminary.OtherBerberine
Plant alkaloid, glucose-metabolism research
Small human trials support metabolic-marker changes; long-term clinical-outcome evidence is limited.OtherNAC (N-Acetylcysteine)
Glutathione precursor antioxidant
Established antidote use; respiratory trial results differ across COPD populations.OtherTaurine
Conditionally essential amino acid
Limited human intervention evidence for selected outcomes; human longevity benefit remains unproven.Drawn from 200 cited sources, reviewed September 2026. Listing a compound is not an endorsement or a claim of regulatory approval. This is a selected-source educational library, not a systematic review.
