kairoby Opportune Labs

104 compounds, with the sources attached.

GLP-1 medicines, peptides, hormones, and supplements, each with what the human evidence measures, what remains unknown, and safety notes. Human trials, animal studies, and lab findings are labeled separately. Identification and education only: no dosing advice, no purchasing links.

Showing all 104 guides

GLP-1 & Metabolic

Semaglutide

GLP-1 receptor agonist (Ozempic/Wegovy)

Randomized human evidence
GLP-1 & Metabolic

Tirzepatide

GIP/GLP-1 dual agonist (Mounjaro/Zepbound)

Randomized human evidence
GLP-1 & Metabolic

Retatrutide

GGG triple agonist, investigational

Human randomized trials
GLP-1 & Metabolic

Liraglutide

Daily GLP-1 agonist (Saxenda/Victoza)

Approved-product clinical evidence
GLP-1 & Metabolic

Cagrilintide

Amylin analog, investigational

Human randomized trials
GLP-1 & Metabolic

Survodutide

Glucagon/GLP-1 dual agonist, investigational

Human randomized trials
GLP-1 & Metabolic

AOD-9604

HGH fragment 176-191 analog

Animal studies; limited clinical certainty
GLP-1 & Metabolic

5-Amino-1MQ

NNMT inhibitor, small molecule

Cell and animal evidence
GLP-1 & Metabolic

MOTS-c

Mitochondrial-derived metabolic peptide

Cell and animal evidence
GLP-1 & Metabolic

Tesofensine

Triple monoamine reuptake inhibitor

Human trial with an Expression of Concern
Healing & Recovery

BPC-157

Body-protection compound, gastric pentadecapeptide

Limited human evidence
Healing & Recovery

TB-500

Thymosin beta-4 fragment

Human evidence not established
Healing & Recovery

BPC-157 / TB-500 blend

BPC-157 and TB-500 combination

Combination evidence limited
Healing & Recovery

GHK-Cu

Copper tripeptide

Preclinical evidence highlighted
Healing & Recovery

KPV

α-MSH fragment, gut & inflammation research

Cell and mouse evidence
Healing & Recovery

ARA-290

EPO-derived research peptide

Early human trials · mixed outcomes
Healing & Recovery

Pentosan Polysulfate

Semi-synthetic glycosaminoglycan

Approved oral product; route-specific evidence
Healing & Recovery

Larazotide

Tight-junction regulator peptide

Human randomized trial evidence
Growth Hormone Axis

CJC-1295 (no DAC)

GHRH analog (Mod GRF 1-29)

Evidence cannot be transferred
Growth Hormone Axis

CJC-1295 (DAC)

Long-acting GHRH analog

Early randomized human studies
Growth Hormone Axis

Ipamorelin

Selective ghrelin-receptor GH secretagogue

Human trial in a different setting
Growth Hormone Axis

CJC-1295 / Ipamorelin

Common combined GH-axis vial

Combination evidence not established
Growth Hormone Axis

Sermorelin

GHRH 1-29 analog

Human physiology; historical product approval
Growth Hormone Axis

Tesamorelin

Stabilized GHRH analog (Egrifta)

Approved indication · product-specific
Growth Hormone Axis

Hexarelin

GH secretagogue hexapeptide

Small human physiology studies
Growth Hormone Axis

GHRP-2

GH-releasing hexapeptide

Small human studies; FDA safety concerns
Growth Hormone Axis

GHRP-6

GH-releasing hexapeptide, appetite effects

Small human physiology studies
Growth Hormone Axis

MK-677 (Ibutamoren)

Oral ghrelin mimetic (non-peptide)

Human randomized trials; important safety signals
Growth Hormone Axis

HGH (Somatropin)

Recombinant human growth hormone

Approved-product clinical evidence
Longevity & Mitochondrial

NAD+

Nicotinamide adenine dinucleotide

Limited human infusion research
Longevity & Mitochondrial

Epithalon

Telomerase-research tetrapeptide

Preclinical research and a small human biomarker study
Longevity & Mitochondrial

SS-31 (Elamipretide)

Mitochondrial-targeted tetrapeptide

Approved indication · accelerated approval
Longevity & Mitochondrial

Humanin

Mitochondrial-derived peptide

Preclinical and observational evidence
Longevity & Mitochondrial

FOXO4-DRI

Senolytic research peptide

Cell and mouse evidence
Longevity & Mitochondrial

GlyNAC

Glycine + N-acetylcysteine combination

Small randomized human trials
Cognitive

Semax

ACTH-derived research peptide

Mainly preclinical evidence in this guide
Cognitive

Selank

Tuftsin-derived research peptide

Limited human and preclinical evidence
Cognitive

Dihexa

Angiotensin IV-derived cognitive research compound

Cell and animal evidence
Cognitive

Cerebrolysin

Porcine-derived neuropeptide preparation

Human trials with mixed results
Cognitive

P21

CNTF-derived research peptide

Preclinical neurotrophic research
Skin, Hair & Tanning

Melanotan I

α-MSH analog (afamelanotide)

Human studies; approved product-specific use
Skin, Hair & Tanning

Melanotan II

α-MSH analog, tanning research

Very limited early human research
Skin, Hair & Tanning

PTD-DBM

Wnt/β-catenin hair-research peptide

Preclinical hair and wound models
Skin, Hair & Tanning

Zn-Thymulin

Zinc-thymulin hair-research complex

Preclinical biology; small exploratory hair report
Immune

Thymosin Alpha-1

Thymic immune-modulating peptide

Human randomized trials exist, including a large negative sepsis trial. Healthy-user prevention and longevity benefits remain unestablished.
Immune

Thymulin

Zinc-dependent thymic hormone

Human physiology evidence; very limited direct evidence for therapeutic thymulin administration.
Immune

LL-37

Human cathelicidin antimicrobial peptide

Topical human trials give mixed results; evidence for systemic wellness treatment is inadequate.
Sexual Health

PT-141 (Bremelanotide)

Melanocortin agonist (Vyleesi)

Two placebo-controlled phase III trials support improvements in desire and related distress for the labeled population.
Sexual Health

Kisspeptin-10

GnRH-axis signaling peptide

Small human physiology studies; therapeutic benefit and long-term safety remain uncertain.
Sexual Health

Oxytocin

Neuropeptide hormone

Established obstetric medicine; small sexual-function trials have not shown a clear advantage over placebo.
Hormones & TRT

Testosterone Cypionate

Injectable testosterone ester

Established replacement use; clinical benefit depends on diagnosis, formulation and the outcome being measured.
Hormones & TRT

Testosterone Enanthate

Injectable TRT ester

Established replacement therapy; product trials largely confirm testosterone exposure rather than universal improvement in wellbeing.
Hormones & TRT

Testosterone Propionate

Short-ester injectable testosterone

Human exposure studies exist, but robust modern head-to-head clinical-outcome evidence is limited.
Hormones & TRT

Testosterone Undecanoate

Long-ester testosterone (Aveed / Jatenzo)

Approved-product trials establish replacement exposure; selected trials assess symptoms in men with documented deficiency.
Hormones & TRT

Testosterone Cream

Transdermal testosterone preparation

Replacement evidence exists, but compounded creams need separate quality and exposure assessment.
Hormones & TRT

Testosterone (female HRT)

Low-dose testosterone in women's HRT

Sexual-function trials exist; long-term safety and broader symptom claims remain uncertain.
Hormones & TRT

Enclomiphene

Oral selective estrogen receptor modulator

Randomized trials demonstrate endocrine effects; clinical-outcome and long-term safety evidence remain incomplete.
Hormones & TRT

Clomiphene (Clomid)

Oral selective estrogen receptor modulator

Established ovulation-induction use; smaller trials support hormone changes in selected men.
Hormones & TRT

Tamoxifen (Nolvadex)

Oral SERM

Strong clinical evidence in defined breast-cancer settings; much smaller studies for other hormone-related uses.
Hormones & TRT

Anastrozole

Aromatase inhibitor — estrogen management

Large oncology trials exist. Male hormone studies show endocrine changes and a meaningful bone-health caution.
Hormones & TRT

HCG

Human chorionic gonadotropin — LH analog

Approved clinical uses in selected reproductive disorders; no established obesity-treatment benefit.
Hormones & TRT

Gonadorelin

GnRH analog

Human fertility evidence exists for specific hypothalamic conditions and controlled pulsatile delivery.
Hormones & TRT

DHEA

Adrenal androgen precursor (oral)

Human trials do not establish broad anti-aging or vitality benefits from routine oral supplementation.
Hormones & TRT

Estradiol

Bioidentical estrogen (patch / injection / cream)

Estrogen therapy has established menopausal symptom benefits; formulation and patient context determine the benefit-risk discussion.
Hormones & TRT

Progesterone

Bioidentical progesterone (oral / cream)

Established oral-product evidence for endometrial protection; symptom studies are more population-specific.
Hormones & TRT

Levothyroxine (T4)

Thyroid hormone replacement

Established hypothyroidism treatment; benefit is less clear in some subclinical presentations.
Hormones & TRT

Liothyronine (T3)

Active thyroid hormone

Established thyroid-hormone activity; adding T3 has not consistently improved patient outcomes in controlled studies.
Sleep

DSIP

Delta sleep-inducing peptide

Small, older human sleep studies
Sleep

Epitalon (nightly)

Pineal-axis tetrapeptide

Preclinical research and a small human biomarker study
Other

L-Carnitine (injectable)

Fatty-acid transport amino acid derivative

Established deficiency-treatment indications; no reliable inference that injecting more produces greater fat loss in someone without deficiency.
Other

Methylene Blue

Mitochondrial electron-cycling compound

Approved antidote use; preliminary human cognition research, without established routine nootropic benefit.
Other

Glutathione

Glutathione tripeptide

Human oral studies show biomarker effects; broad wellness outcomes and injectable equivalence remain unestablished.
Other

B12 (Methylcobalamin)

Injectable B-vitamin

Established vitamin-deficiency biology; separate, disease-specific methylcobalamin research does not validate generic energy claims.
Other

Lipo-C (MIC + B12)

Lipotropic injection blend

Ingredient physiology exists; convincing controlled weight-loss evidence for the exact blend was not identified.
GLP-1 & Metabolic

Mazdutide

GLP-1 / glucagon dual agonist, investigational

Human phase 3 evidence
GLP-1 & Metabolic

Orforglipron

Oral GLP-1 agonist; Foundayo is an approved product

FDA-approved product; phase 3 trials
GLP-1 & Metabolic

Pramlintide

Amylin analog (Symlin)

Approved-product evidence
GLP-1 & Metabolic

Ecnoglutide

GLP-1 receptor agonist, investigational

Human phase 3 evidence
GLP-1 & Metabolic

SLU-PP-332

ERR agonist research compound

Cell and mouse evidence
Healing & Recovery

Pentadeca Arginate (PDA)

BPC-related arginate formulation

Developer announcement; clinical evidence gap
Healing & Recovery

VIP

Vasoactive intestinal peptide

Human trials; results depend on setting and route
Healing & Recovery

Thymosin Beta-4

Full-length thymosin beta-4 peptide

Study-specific evidence
Growth Hormone Axis

MGF

Mechano growth factor (IGF-1 splice variant)

Conflicting cell and animal evidence
Growth Hormone Axis

PEG-MGF

PEGylated long-acting mechano growth factor

Preclinical context; direct human evidence gap
Growth Hormone Axis

IGF-1 LR3

Long-acting insulin-like growth factor analog

Animal pharmacology
Growth Hormone Axis

IGF-1 DES

Shortened IGF-1 variant

Animal pharmacology
Growth Hormone Axis

Follistatin 344

Myostatin-binding research protein

Early human gene-therapy study; product mismatch
Longevity & Mitochondrial

Rapamycin (Sirolimus)

mTOR inhibitor, longevity research

Prescription evidence; early aging trials
Longevity & Mitochondrial

Metformin

Biguanide, metabolic & longevity research

Established diabetes use; uncertain longevity benefit
Longevity & Mitochondrial

NMN

Nicotinamide mononucleotide (NAD+ precursor)

Early human metabolic research
Longevity & Mitochondrial

Nicotinamide Riboside

NAD+ precursor vitamin B3 derivative

Randomized human studies; mixed outcomes
Longevity & Mitochondrial

Spermidine

Polyamine investigated in autophagy research

Randomized human evidence; memory benefit uncertain
Longevity & Mitochondrial

Fisetin

Flavonoid investigated in senescence research

Preclinical senescence research and limited human clinical studies
Longevity & Mitochondrial

Urolithin A

Gut metabolite investigated in mitochondrial research

Randomized human muscle trials
Cognitive

Bromantane

Bromantane research compound

Limited clinical and laboratory studies
Cognitive

Noopept

Nootropic dipeptide research compound

Limited clinical and preclinical evidence
Cognitive

Cortexin

Porcine cortical neuropeptide preparation

Limited human stroke trials
Skin, Hair & Tanning

SNAP-8

Acetyl octapeptide-3, topical anti-wrinkle research

Manufacturer-led cosmetic evidence
Skin, Hair & Tanning

Argireline

Acetyl hexapeptide-8, topical cosmetic peptide

Small randomized topical studies
Immune

Thymogen

Glutamyl-tryptophan immune dipeptide

Small, older human studies; little independently replicated evidence for contemporary wellness claims.
Immune

Thymalin

Thymic peptide immune-regulating preparation

Limited clinical reports with important design and reporting uncertainty; mechanistic findings are preliminary.
Other

Berberine

Plant alkaloid, glucose-metabolism research

Small human trials support metabolic-marker changes; long-term clinical-outcome evidence is limited.
Other

NAC (N-Acetylcysteine)

Glutathione precursor antioxidant

Established antidote use; respiratory trial results differ across COPD populations.
Other

Taurine

Conditionally essential amino acid

Limited human intervention evidence for selected outcomes; human longevity benefit remains unproven.
No compound matches that yet. Kairo also tracks custom compounds, or tell us what to add.

Drawn from 200 cited sources, reviewed September 2026. Listing a compound is not an endorsement or a claim of regulatory approval. This is a selected-source educational library, not a systematic review.

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